We collaborate with academia and industry to help commercialize their early-stage drug therapy concepts.
TSRL, Inc. partners with academic researchers on SBIR/STTR grants in areas where our interests overlap. As experienced SBIR PIs, partnering with us offers several advantages to improve the overall chances of your project receiving an award, as well as maximizing its scope and duration. Due to these reasons we have obtained a higher-than-average success rate for funding awards over the last ten years.
- PI/collaborator network
- Commercialization writing
- Technology de-risking strategies
- Wet lab space and AAALAC-accredited animal laboratories
- Preliminary data generation
Types of Grants:
- SBIR Phase I/II/III
- NIH contracts
- Program grants (i.e. UO1)
PK/PD and ADME
TSRL, Inc. has strong expertise in preclinical pharmacokinetic/dynamic (PK/PD), metabolism and biopharmaceutics studies designed to define human drug delivery strategies and dosing regimen.
Permeability and Absorption Assays (links)
- Permeability Classification in the Rat In Situ Perfusion Model
- Permeability Screening in the MDCK Cell Tissue Culture Model
Pharmacokinetic Studies in Rat and Mice
Solubility Determination and Dissolution Testing
Our research is conducted in a 7,200 sq. ft. facility of which 5,000 sq. ft. is wet lab space, with on-site analytical chemistry, formulation, cell culture equipment and capabilities. Office space and administrative support is also available.
Some of Our On-Site Equipment Includes:
- Safety Cabinets & Fume Hoods
- Computer Controlled Gradient LC/MS/MS Systems
- HPLC Systems
- Clinical and Micro Centrifuges
- Microplate Readers
- Anesthesia Stations
- Liquid Handling Systems
- Tissue Culture Incubators
Marketing and Business Development
As a part of our grant-writing process and commitment to maximizing commercial potential, TSRL Inc. will contribute resources on a per-project basis to business development and marketing. We have qualified professionals to establish a web presence for our partner companies. Likewise, we leverage our extensive networks to grow a stakeholder web around your technology, so it receives the support it needs to thrive.