PK/ADME and Toxicology Services

Understanding Drug Behavior to Inform Smarter Decisions

As a science-first preclinical CRO, TSRL offers PK/ADME and toxicology services that help drug developers understand how their compounds behave in the body. These studies are critical for guiding formulation, selecting dose levels, and supporting early go or no-go decisions.

Our team delivers clear, data-backed insights that help move promising compounds forward with greater confidence.

 

PK/ADME and Toxicology Capabilities

  • In vitro ADME studies including absorption, metabolism, and excretion

  • Microsome, hepatocyte, and intestinal metabolic stability testing

  • Permeability and transporter studies

  • In vivo PK studies with various routes of administration

  • Exploratory toxicology

  • Bioanalytical support for exposure assessments

These services are coordinated within TSRL’s broader preclinical workflow, giving your team access to integrated formulation, testing, and modeling support under one roof.

 

Why Choose TSRL for PK and Toxicology Studies

  • Strategic study design that aligns with early development goals

  • Experienced scientific team with deep knowledge of ADME modeling and interpretation

  • Custom assay support for novel compounds and delivery strategies

  • Fast, reliable data turnaround to keep programs on schedule

Our PK/ADME and toxicology services are designed to provide the answers teams need quickly, with the flexibility to adapt as priorities shift.

 

Clients are Saying

 

“TSRL will make an outstanding team to bring forward much needed therapeutics to combat the spreading problem of multi-drug resistant infectious diseases.”

Frederick S. Buckner, MD
University of Washington School of Medicine

 

Let's Talk About Your Program

Connect with a TSRL scientist to learn how we can support your goals with strategic, science-driven solutions by filling out this form.