In TSRL's Hydrophilic Solubilization Technology (HST), Gelatin, a naturally derived collagen extract carrying both positive and negative charges, coats the particles of the API and prevents their aggregation or clumping. This results in an improved wettability of hydrophobic drug particles through polar interactions. In addition, the amphiphilic lecithin reduces surface tension between the dissolution fluid and the particle surface.
In TSRL's Hydrophilic Solubilization Technology (HST), Gelatin, a naturally derived collagen extract carrying both positive and negative charges, coats the particles of the API and prevents their aggregation or clumping. This results in an improved wettability of hydrophobic drug particles through polar interactions. In addition, the amphiphilic lecithin reduces surface tension between the dissolution fluid and the particle surface.