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Patents

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International Bioequivalence Standards: A New Era
by Gordon Amidon, Lawrence Lesko, Kaml Midha, Vinod Shah and John Hilfinger
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Membrane Transporters As Drug Targets (Pharmaceutical Biotechnology, V. 12)
by Gordon L. Amidon(Editor). Hardcover (January 2000)
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Chemical Stability of Pharmaceuticals : A Handbook for Pharmacists
by Kenneth A. Connors, et al. Paperback (September 1986)
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Transport Processes in Pharmaceutical Systems (Drugs and the Pharmaceutical Sciences, V. 102)
by Gordon L. Amidon(Editor), et al. Hardcover (June 2000)
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Peptide-Based Drug Design : Controlling Transport and Metabolism (Professional Reference Book)
by Michael D. Taylor, Gordon L. Amidon (Editor). Hardcover (December 1994)
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Pharmacokinetic Analysis : A Practical Approach
by Peter I. D. Lee, et al. Hardcover (July 1996)
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Mechanisms of Drug Interactions (Handbook of Experimental Pharmacology, Vol 122)
by Gordon L. Amidon(Editor), et al. Hardcover (June 1996)
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We have an active research program covering a wide range of topics related to oral and parenteral drug delivery. Listed below are selected references and patents describing work that has been done in our laboratories and those of our collaborators:

Issued Patents

7,176,185 - Short Peptide Carrier System for Cellular Delivery of Agent.  Issued February 13, 2007

6,669,954 - Controlled Release of Drugs.  Issued December 30, 2003

6,207,191 - Multi-stage Drug Delivery System.  Issued March 27, 2001

6,153,592 -Enhancing the Bioavailability of Proteolytically Labile
Therapeutic Agents.  Issued November 28, 2000

6,048,551 -Microsphere Encapsulation of Gene Transfer Vectors. 
Issued April 11, 2000

5,993,858 -Method and Formulation for Increasing the Bioavailability of Poorly Water-soluble Drugs.  Issued November 30, 1999

5,976,571 -Method for Making a Multi-stage Drug Delivery System.  Issued November 2, 1999

5,851,275 -Water Soluble Pharmaceutical Coating and Method for Producing Coated Pharmaceuticals.  Issued December 22, 1998

5,834,022 -Water Soluble Pharmaceutical Coating and Method for Producing Coated Pharmaceuticals.  Issued November 10, 1998

5,686,133 -Water Soluble Pharmaceutical Coating and Method for Producing Coated Pharmaceuticals.  Issued November 11, 1997

5,674,530 - Method for Making a Multi-stage Drug Delivery System.  Issued October 7, 1997

5,569,452 -Pharmaceutical Formulation Having Enhanced Bile Acid Binding Affinity.  Issued October 29, 1996

5,387,421 - Multi-stage Drug Delivery System.  Issued February 7, 1995

5,229,131 -Pulsatile Drug Delivery System.  Issued July 20, 1993

Applications

20080026077 - Methods and Compositions of Gene Delivery Agents for Systemic and Local Therapy.  Published January 31, 2008

WO2007/112348 - Prodrugs Composition.  Published October 4, 2007

20070167353 - Prodrug Composition.  Published July 19, 2007

WO2007/067779 - Methods and Compositions of Drug delivery Enhancement.  Published June 14, 2007.

20060276402 - Synthetic Peptide Inhibitors of Thrombin and Thrombin Activation of Protease Activated Receptors 1 & 4.  Published December 7, 2006

20050220876 - Methods and Composition of Extended Delivery of Water Insoluble Drugs.   Published October 6, 2005

20050137141 - Prodrug Composition.  Published June 23, 2005

20050026859 - Methods and Compositions of Gene Delivery Agents for Systemic and Local Therapy.  Published February 3, 2005